I-motif-based nano-flares for sensing pH changes in live cells

Chem Commun (Camb). 2014 Dec 25;50(99):15768-71. doi: 10.1039/c4cc08054h. Epub 2014 Nov 5.

Abstract

Here, we report an intracellular probe termed i-motif-based nano-flares. They could sense pH change in a live cell since they combine cellular transfection, enzymatic protection, and pH detection.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antimalarials / chemistry
  • Antimalarials / metabolism
  • Gold / chemistry
  • HeLa Cells
  • Humans
  • Hydrogen-Ion Concentration
  • Lysosomes / metabolism
  • Metal Nanoparticles / chemistry
  • Microscopy, Confocal
  • Nanostructures / chemistry*
  • Oligonucleotides / chemistry
  • Rhodamines / chemistry
  • Temperature
  • Transfection

Substances

  • Antimalarials
  • Oligonucleotides
  • Rhodamines
  • Gold