Sarcopenia: a predictor of mortality and the need for early diagnosis and intervention

Aging Clin Exp Res. 2015 Jun;27(3):249-54. doi: 10.1007/s40520-014-0281-4. Epub 2014 Nov 4.

Abstract

The term sarcopenia refers to the loss of muscle mass that occurs with aging. Sarcopenia is defined by the European Working Group on Sarcopenia in Older People (EWGSOP) as low muscle mass and low muscle function (strength and performance). Its prevalence varies depending on the definition used for it, but estimates propose a loss of approximately 8 % per decade until the age of 70 years; afterwards, the loss increases and ranges from 13 to 24 % per decade. Irrespective of how sarcopenia is defined, both low muscle mass and poor muscle strength are highly prevalent and important risk factors for disability and increased mortality in individuals as they age. In this review, we address age-related muscle loss and the risk factors of mortality, emphasizing the need for early diagnosis and intervention.

Publication types

  • Review

MeSH terms

  • Aging / physiology*
  • Disabled Persons
  • Early Diagnosis
  • Early Medical Intervention
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muscle Strength
  • Muscle, Skeletal / pathology
  • Muscle, Skeletal / physiopathology
  • Prevalence
  • Risk Factors
  • Sarcopenia* / diagnosis
  • Sarcopenia* / mortality