Perceived discrimination has been shown to be strongly associated with mental health outcomes, such as depression, anxiety, chronic stress, post traumatic stress disorder, and low self-esteem. This study (N = 88) examined the effects of perceived discrimination and its association with child mental health symptoms. African American children had a significantly stronger association between social stress and a sense of exclusion/rejection than Multiracial or European American children. Nurses need to assess and counsel families of color about their experiences with perceived discriminatory acts.