EQ-5D-3L derived population norms for health related quality of life in Sri Lanka

PLoS One. 2014 Nov 3;9(11):e108434. doi: 10.1371/journal.pone.0108434. eCollection 2014.

Abstract

Background: Health Related Quality of Life (HRQoL) is an important outcome measure in health economic evaluation that guides health resource allocations. Population norms for HRQoL are an essential ingredient in health economics and in the evaluation of population health. The aim of this study was to produce EQ-5D-3L-derived population norms for Sri Lanka.

Method: A population sample (n = 780) was selected from four districts of Sri Lanka. A stratified cluster sampling approach with probability proportionate to size was employed. Twenty six clusters of 30 participants each were selected; each participant completed the EQ-5D-3L in a face-to-face interview. Utility weights for their EQ-5D-3L health states were assigned using the Sri Lankan EQ-5D-3L algorithm. The population norms are reported by age and socio-economic variables.

Results: The EQ-5D-3L was completed by 736 people, representing a 94% response rate. Sixty per cent of the sample reported being in full health. The percentage of people responding to any problems in the five EQ-5D-3L dimensions increased with age. The mean EQ-5D-3L weight was 0.85 (SD 0.008; 95%CI 0.84-0.87). The mean EQ-5D-3L weight was significantly associated with age, housing type, disease experience and religiosity. People above 70 years of age were 7.5 times more likely to report mobility problems and 3.7 times more likely to report pain/discomfort than those aged 18-29 years. Those with a tertiary education were five times less likely to report any HRQoL problems than those without a tertiary education. A person living in a shanty was 4.3 more likely to have problems in usual activities than a person living in a single house.

Conclusion: The population norms in Sri Lanka vary with socio-demographic characteristics. The socioeconomically disadvantaged have a lower HRQoL. The trends of population norms observed in this lower middle income country were generally similar to those previously reported in high income countries.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Epidemiologic Factors
  • Female
  • Health / statistics & numerical data*
  • Humans
  • Male
  • Middle Aged
  • Odds Ratio
  • Public Health Surveillance*
  • Quality of Life*
  • Sex Factors
  • Sri Lanka / epidemiology
  • Surveys and Questionnaires
  • Young Adult

Grants and funding

This work was funded by Griffith University Post Graduate Research Scholarship and Griffith University International Postgraduate Research Scholarship. The data collection was partly funded by a research grant from the Population and Social Health Research Programme, Griffith University. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.