Flow control using Scepter™ balloons for Onyx embolization of a vein of Galen aneurysmal malformation

Childs Nerv Syst. 2015 Jan;31(1):135-40. doi: 10.1007/s00381-014-2576-3. Epub 2014 Oct 31.

Abstract

Purpose: We present a technical development of the endovascular treatment technique for vein of Galen aneurysmal malformation, using Onyx™ (ethylene vinyl alcohol copolymer) delivered under flow control through double-lumen balloon microcatheters.

Materials and methods: An 11-month-old patient that initially presented with increasing head circumference was diagnosed with mural type vein of Galen aneurysmal malformation. Complete cure was obtained in a single endovascular treatment session. Onyx was delivered simultaneously through two double-lumen balloon microcatheters (Scepter™, Microvention, Terumo Group). In both arterial feeders, balloon inflation occluded the high-flow arterial-venous shunting and thus facilitated the controlled propagation of the embolic product in the afferent artery and the shunt point while preventing distal migration into the venous system.

Results: Two years post-procedure, MR imaging showed persistent occlusion of arterial-venous shunts with complete regression of the venous dilatation. On clinical examination, the patient had no neurological deficits, and no cognitive impairment was detected at neuropsychological testing.

Conclusion: The use of double-lumen balloon microcatheters for flow control during delivery of Onyx represents a viable alternative for the endovascular treatment of vein of Galen aneurysmal malformations.

Publication types

  • Case Reports

MeSH terms

  • Embolization, Therapeutic / methods*
  • Humans
  • Infant
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Male
  • Polyvinyls / therapeutic use*
  • Treatment Outcome
  • Vein of Galen Malformations / surgery*
  • Vertebral Artery / pathology

Substances

  • Polyvinyls
  • ethylene-vinyl alcohol copolymer