Abstract
Eight bibenzyl derivatives, namely dendrocandins J-Q (1-8), were isolated from the stems of Dendrobium candidum. Their structures were elucidated by 1D and 2D NMR experiments and mass spectrometry. Compounds 1-8 were examined for antioxidant activity by 1,1-diphenyl-2-picrylhydrazyl free radical scavenging assay, and the IC50 values were 36.8, 70.2, 45.0, 60.5, 87.6, 50.4, 22.3, and 30.3 μM, respectively.
Keywords:
Dendrobium candidum; antioxidant activity; bibenzyl derivatives; dendrocandins J–Q.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antioxidants / chemistry
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Antioxidants / isolation & purification*
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Antioxidants / pharmacology
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Bibenzyls / chemistry
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Bibenzyls / isolation & purification*
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Biphenyl Compounds / pharmacology
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Dendrobium / chemistry*
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / isolation & purification*
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Free Radical Scavengers / pharmacology
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Inhibitory Concentration 50
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Picrates / pharmacology
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Plant Stems / chemistry
Substances
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Antioxidants
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Bibenzyls
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Biphenyl Compounds
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Drugs, Chinese Herbal
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Free Radical Scavengers
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Picrates
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1,1-diphenyl-2-picrylhydrazyl