Complete mitochondrial genome sequence and mutations of the liver cancer model inbred C57BL/6 mice strain

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 May;27(3):1999-2000. doi: 10.3109/19401736.2014.974160. Epub 2014 Oct 28.

Abstract

In the present work, we undertook the complete mitochondrial genome sequencing of an important liver cancer model inbred rat strain for the first time. The total length of the mitogenome was 16,308 bp. It harbored 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes and 1 non-coding control region (D-loop region). The mutation events were also reported.

Keywords: Genome; liver cancer; mitochondrion.

MeSH terms

  • Animals
  • Base Pairing / genetics
  • Base Sequence
  • DNA, Mitochondrial / genetics
  • Disease Models, Animal
  • Female
  • Genome, Mitochondrial*
  • Liver Neoplasms / genetics*
  • Mice, Inbred C57BL
  • Mutation / genetics*

Substances

  • DNA, Mitochondrial