[Hypoxic hepatitis]

Ugeskr Laeger. 2014 Jan 20;176(4A):V08130501.
[Article in Danish]

Abstract

Hypoxic hepatitis (HH), also known as ischaemic hepatitis or shock liver, is an acute liver injury caused by hepatic hypoxia. Cardiac failure, respiratory failure and septic shock are the main underlying conditions. In each of these conditions, several haemodynamic mechanisms lead to hepatic hypoxia. A shock state is observed in only 50% of cases. Thus, shock liver and ischaemic hepatitis are misnomers. HH can be a diagnostic pitfall but the diagnosis can be established when three criteria are met. Prognosis is poor and prompt identification and treatment of the underlying conditions are crucial.

Publication types

  • Review

MeSH terms

  • Heart Failure / complications
  • Heart Failure / physiopathology
  • Hepatitis / diagnosis
  • Hepatitis / etiology*
  • Hepatitis / physiopathology
  • Humans
  • Hypoxia / diagnosis
  • Hypoxia / etiology*
  • Hypoxia / physiopathology
  • Respiratory Insufficiency / complications
  • Respiratory Insufficiency / physiopathology
  • Risk Factors
  • Shock, Septic / complications
  • Shock, Septic / physiopathology