Meal-induced blood pressure fall in patients with isolated morning hypertension

Clin Exp Hypertens. 2015;37(5):364-8. doi: 10.3109/10641963.2014.972564. Epub 2014 Oct 27.

Abstract

We aimed to determine a possible association between isolated morning hypertension (IMH) and meal-induced blood pressure (BP) fall in adult treated hypertensive patients who underwent home BP measurements. A total of 230 patients were included, median age 73.6, 65.2% women. After adjusting for age, sex, number of antihypertensive drugs, office and home BP levels, the association between IMH and meal-induced BP fall was statistically significant. In conclusion, meal-induced BP fall and IMH detected through home blood pressure monitoring (HBPM) are independently associated in hypertensive patients. The therapeutic implications of such observation need to be clarified in large-scale prospective studies.

Keywords: Home blood pressure; hypertension; isolated morning hypertension; postprandial blood pressure; postprandial hypotension.

MeSH terms

  • Aged
  • Antihypertensive Agents / therapeutic use
  • Blood Pressure / physiology*
  • Blood Pressure Monitoring, Ambulatory
  • Female
  • Follow-Up Studies
  • Humans
  • Hypertension / drug therapy
  • Hypertension / physiopathology*
  • Hypotension / etiology*
  • Hypotension / physiopathology
  • Male
  • Meals / physiology*
  • Postprandial Period / physiology*
  • Prospective Studies
  • Time Factors

Substances

  • Antihypertensive Agents