Genomic medicine for cancer diagnosis

J Surg Oncol. 2015 Jan;111(1):24-30. doi: 10.1002/jso.23778. Epub 2014 Oct 24.

Abstract

Genomic diagnostics in cancer has evolved since the completion of the Human Genome Project and the advancements made in diagnosis and therapy in chronic myelogenous leukemia. Among the diseases to achieve limited success or potentially benefit from diagnostic genetic testing are thyroid cancer, Burkitt's lymphoma, gastrointestinal stromal tumors, adrenocortical carcinoma, and colorectal cancer. With increased understanding of genomics, genetic tests should improve diagnosis and help guide medical and surgical management.

Keywords: Burkitt's lymphoma; diagnostic genomics; gastrointestinal stromal tumors; genetic testing; thyroid cancer.

Publication types

  • Review

MeSH terms

  • Genetic Predisposition to Disease
  • Genetic Testing*
  • Genomics*
  • Humans
  • Neoplasms / diagnosis*
  • Neoplasms / genetics*