Aurophilically cross-linked "dynamic" hydrogels mimicking healthy synovial fluid properties

Chem Commun (Camb). 2014 Dec 14;50(96):15199-201. doi: 10.1039/c4cc05735j.

Abstract

We report a new supramolecular dynamic hydrogel, based on a new concept of reversible aurophilic cross-linkers, mimicking the rheological behaviour of healthy synovial fluid under physiological conditions with good cell viability.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line
  • Cell Survival
  • Cross-Linking Reagents / chemistry
  • Gold / chemistry*
  • Humans
  • Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry*
  • Hydrogel, Polyethylene Glycol Dimethacrylate / pharmacology
  • Hydrogen-Ion Concentration
  • Polyethylene Glycols / chemistry
  • Rheology
  • Synovial Fluid / chemistry*

Substances

  • Cross-Linking Reagents
  • Hydrogel, Polyethylene Glycol Dimethacrylate
  • Polyethylene Glycols
  • Gold