A practical method for the detection of freezing of gait in patients with Parkinson's disease

Clin Interv Aging. 2014 Oct 8:9:1709-19. doi: 10.2147/CIA.S69773. eCollection 2014.

Abstract

Purpose: Freezing of gait (FOG), increasing the fall risk and limiting the quality of life, is common at the advanced stage of Parkinson's disease, typically in old ages. A simple and unobtrusive FOG detection system with a small calculation load would make a fast presentation of on-demand cueing possible. The purpose of this study was to find a practical FOG detection system.

Patients and methods: A sole-mounted sensor system was developed for an unobtrusive measurement of acceleration during gait. Twenty patients with Parkinson's disease participated in this study. A simple and fast time-domain method for the FOG detection was suggested and compared with the conventional frequency-domain method. The parameters used in the FOG detection were optimized for each patient.

Results: The calculation load was 1,154 times less in the time-domain method than the conventional method, and the FOG detection performance was comparable between the two domains (P=0.79) and depended on the window length (P<0.01) and dimension of sensor information (P=0.03).

Conclusion: A minimally constraining sole-mounted sensor system was developed, and the suggested time-domain method showed comparable FOG detection performance to that of the conventional frequency-domain method. Three-dimensional sensor information and 3-4-second window length were desirable. The suggested system is expected to have more practical clinical applications.

Keywords: Parkinson’s disease; acceleration; detection system; freezing of gait; frequency-domain; time-domain.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acceleration*
  • Accelerometry / instrumentation
  • Accidental Falls
  • Aged
  • Aged, 80 and over
  • Female
  • Gait Apraxia / complications
  • Gait Apraxia / diagnosis*
  • Gait Apraxia / psychology
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease / complications
  • Parkinson Disease / diagnosis*
  • Parkinson Disease / psychology
  • Quality of Life / psychology
  • Risk Factors
  • Signal Processing, Computer-Assisted / instrumentation
  • Weight-Bearing