Abstract
A new cinchona alkaloid derived bifunctional tertiary amine-phosphoramide is identified as a highly enantioselective catalyst for Michael addition of both unprotected 3-arylthio- and 3-alkylthiooxindoles to nitroolefins. The phosphoramide moiety of plays an indispensable role in this reaction.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkenes / chemistry*
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Catalysis
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Cinchona Alkaloids / chemistry*
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Indoles / chemistry*
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Phosphoramides / chemistry*
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Stereoisomerism
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Sulfhydryl Compounds / chemistry*
Substances
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Alkenes
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Cinchona Alkaloids
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Indoles
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Phosphoramides
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Sulfhydryl Compounds
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phosphoramide