Cephalometric analysis is frequently used in orthodontics for diagnostic purposes, in order to evaluate the positional relationship of the upper and lower jaw to the cranial base, as well as to objectively asses the way dental arches relate to one another and to the skeletal base. As with other dento-skeletal anomalies, the normal growth process can induce changes in these parameters. The purpose of this study is to evaluate the skeletal and dental changes that occur in growing patients with Angle Class II division 2 malocclusion. The study also focuses on analyzing and comparing several parameters in three groups of young patients of different ages, diagnosed with Class II division 2 malocclusion, in order to determine whether the anomaly worsens or improves during the patients' growth period. A total of 25 lateral skull teleradiographs were analyzed using cephX. The patients were divided into three groups (Group 1: 6-8 years, Group 2: 9-14 years, Group 3: 15-18 years). We used the cephalometric parameters described in Björk-Jarabak and Tweed analyses, as well as the relationship of the upper and lower central incisors to the skeletal landmarks. The statistical methods used in this study were the analysis of variance (ANOVA) and the unpaired Student's t-test (p<0.05). We concluded that, during the physiological growth process, the Angle Class II division 2 malocclusion has the following cephalometric characteristics: the maxillary central incisors were in accentuated retroclination, the interincisal angle was very obtuse, the gonial angle showed lower than normal values towards the end of the growth period, the lower anterior face height was definitely decreased, the mandibular body length was shorter than normal in the early growth period and the tendency towards a hypodivergent skeletal pattern remained stable during growth.