Feasibility of transoral robotic-assisted high-resolution microendoscopic imaging of oropharyngeal squamous cell carcinoma

Head Neck. 2015 Aug;37(8):E99-102. doi: 10.1002/hed.23892. Epub 2015 Jun 18.

Abstract

Background: Transoral robotic-assisted oncologic surgery of the head and neck offers promising functional results. Nonetheless, the efficacy of oncologic surgery remains critically dependent on obtaining negative margins. We aimed to integrate a miniaturized high-resolution fiber-optic microendoscope (HRME), which provides real-time histological assessment, with the da Vinci robotic system (Intuitive Surgical, Sunnyvale, CA).

Methods: Three patients undergoing transoral robotic surgery (TORS) were prospectively enrolled in this study. Optical imaging of the oropharynx was performed intraoperatively with the robotic-assisted HRME.

Results: All patients underwent the procedure successfully with no complications. The HRME was successfully integrated with the da Vinci robotic system. Several sites of the oropharynx and associated malignancy were imaged, which correlated with the standard histopathological analysis.

Conclusion: Transoral robotic-assisted HRME imaging of the oropharynx is a safe and technically feasible approach, providing a real-time histological assessment and may serve as a valuable aid in oncologic surgery.

Keywords: high-resolution fiber-optic microendoscope (HRME); microendoscopy; optical imaging; oropharynx; squamous cell carcinoma; transoral robotic surgery.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery*
  • Endoscopes*
  • Feasibility Studies
  • Fiber Optic Technology
  • Humans
  • Image Enhancement*
  • Microscopy / instrumentation
  • Mouth
  • Natural Orifice Endoscopic Surgery / instrumentation*
  • Natural Orifice Endoscopic Surgery / methods
  • Neck Dissection
  • Oropharyngeal Neoplasms / pathology
  • Oropharyngeal Neoplasms / surgery*
  • Prospective Studies
  • Robotics*
  • Sensitivity and Specificity
  • Treatment Outcome