Abstract
A Rh(III) catalysed amino arylation of alkynes using copper as the terminal oxidant for regeneration of the catalytically active species under aerobic conditions is described. This novel C-H activation reaction was applied to the synthesis of a wide range of substituted indoles from N-arylureas.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Alkynes / chemistry*
-
Catalysis
-
Copper / chemistry
-
Indoles / chemical synthesis*
-
Oxidants / chemistry
-
Rhodium / chemistry*
-
Urea / analogs & derivatives*
-
Urea / chemistry*
Substances
-
Alkynes
-
Indoles
-
Oxidants
-
Copper
-
Urea
-
Rhodium