HLA-DP1 matching: are we there yet?

Blood. 2014 Oct 16;124(16):2476-7. doi: 10.1182/blood-2014-09-599225.

Abstract

In this issue of Blood, Pidala et al report that nonpermissive DPB1 allele mismatch is associated with increased transplant-related mortality (TRM) and should be avoided to secure optimal unrelated donor hematopoietic stem cell transplantations (HSCTs).

Publication types

  • Comment

MeSH terms

  • Female
  • HLA-DP beta-Chains / immunology*
  • Hematopoietic Stem Cell Transplantation / methods*
  • Hematopoietic Stem Cell Transplantation / mortality*
  • Histocompatibility Testing*
  • Humans
  • Leukemia / therapy*
  • Male
  • Myelodysplastic Syndromes / therapy*

Substances

  • HLA-DP beta-Chains
  • HLA-DPB1 antigen