CD18 (ITGB2) expression in chronic lymphocytic leukaemia is regulated by DNA methylation-dependent and -independent mechanisms

Br J Haematol. 2015 Apr;169(2):286-9. doi: 10.1111/bjh.13188. Epub 2014 Oct 17.

Authors

Evelyn Hutterer¹, Daniela Asslaber, Chiara Caldana, Peter W Krenn, Antonella Zucchetto, Valter Gattei, Richard Greil, Tanja N Hartmann

Affiliation

¹ Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Centre, Paracelsus Medical University, Salzburg, Austria; Salzburg Cancer Research Institute, Salzburg, Austria.

No abstract available

Keywords: DNA methylation; LFA-1 (CD11A/CD18;ITGAL/ITGB2); chronic lymphocytic leukaemia (CLL); microenvironment; proliferation.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

CD18 Antigens / genetics*
CD18 Antigens / metabolism
DNA Methylation*
Gene Expression Regulation, Leukemic*
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
Leukemia, Lymphocytic, Chronic, B-Cell / metabolism

Substances

CD18 Antigens

Grants and funding