Management of Breathlessness in Patients With Advanced Cancer: A Narrative Review

Am J Hosp Palliat Care. 2016 Apr;33(3):286-90. doi: 10.1177/1049909114554796. Epub 2014 Oct 15.

Abstract

Breathlessness is defined as "a subjective experience of breathing discomfort that consists of qualitatively distinct sensations that vary in intensity." It is a common and distressing symptom reported by patients with advanced malignancy. It occurs in up to 70% of patients with advanced cancer, and the symptom is aggravated with disease progression. This article reviews the etiology, assessment, and measurement of dyspnea in patients with advanced cancer. Because of its complex biopsychological etiology and manifestations, multidisciplinary approach with combination of both pharmacological and nonpharmacological interventions provides the best treatment plan for patients with dyspnea.

Keywords: breathlessness; cancer; dyspnea; multidisciplinary; palliative.

Publication types

  • Review

MeSH terms

  • Analgesics, Opioid / therapeutic use
  • Benzodiazepines / therapeutic use
  • Counseling / methods
  • Disease Progression
  • Dyspnea / etiology*
  • Dyspnea / psychology
  • Dyspnea / therapy*
  • Humans
  • Mind-Body Therapies / methods
  • Neoplasms / complications*
  • Oxygen Inhalation Therapy / methods
  • Palliative Care / methods*

Substances

  • Analgesics, Opioid
  • Benzodiazepines