Consensus statement on the immunohistochemical detection of ocular lymphatic vessels

Invest Ophthalmol Vis Sci. 2014 Oct 14;55(10):6440-2. doi: 10.1167/iovs.14-15638.

Abstract

There is currently considerable controversy about existence and classification of "lymphatic vessels" in the eye. Some of the confusion is certainly caused by inappropriate use (or nonuse) of the correct immunohistochemical markers. Many experts in the field expressed the need for a consensus statement, and, in this perspective, authors offer arguments and solutions to reliably continue with immunohistochemical ocular lymphatic research.

Keywords: immune privilege; immunocytochemistry; lymphatics.

Publication types

  • Review

MeSH terms

  • Biomarkers / analysis*
  • Consensus
  • Eye / blood supply*
  • Humans
  • Immunohistochemistry / methods*
  • Lymphatic Vessels / chemistry*
  • Lymphatic Vessels / immunology

Substances

  • Biomarkers