[Drug management of agitation in emergency departments: theoretical recommendations and studies of practices]

Presse Med. 2015 Jan;44(1):20-6. doi: 10.1016/j.lpm.2014.04.027. Epub 2014 Oct 11.
[Article in French]

Abstract

Management of agitation is a frequent problematic of emergency departments that often leads to feelings of insecurity among clinicians. There are various practices regarding the drugs to be used in the management of agitations. Guidelines have been proposed by different groups of experts concerning the antipsychotic drugs that should be used for agitations in psychiatric conditions. Nevertheless, there is no clear-cut procedure referring to the utilization of intramuscular drugs in this situation. Moreover, there is no comparison available between the commonly used medications and other drugs, both in terms of superiority of efficacy and tolerance. In order to accurately assess these practices, evaluation protocols must minimize the interference with the service organization and the routine care. Further studies are required in order to develop guidelines about medications that have to be used to handle agitations, which must be based on robust evidence and applicable to emergency services.

Publication types

  • Review

MeSH terms

  • Antipsychotic Agents / administration & dosage
  • Benzodiazepines / administration & dosage
  • Critical Care / methods*
  • Critical Care / standards
  • Critical Care / statistics & numerical data
  • Drug Interactions
  • Drug Therapy, Combination / statistics & numerical data
  • Emergency Service, Hospital
  • Emergency Services, Psychiatric*
  • Guideline Adherence / statistics & numerical data
  • Humans
  • Injections, Intramuscular
  • Practice Guidelines as Topic*
  • Practice Patterns, Physicians'* / statistics & numerical data
  • Psychomotor Agitation / drug therapy*
  • Psychomotor Agitation / epidemiology

Substances

  • Antipsychotic Agents
  • Benzodiazepines