Structure and antioxidant activity of phenolic compounds isolated from the edible fruits and stem bark of Harpephyllum caffrum

J Environ Sci Health B. 2014;49(12):938-44. doi: 10.1080/03601234.2014.951578.

Abstract

Antioxidant activity in edible fruits is an important characteristic in the choice of fruits for human consumption, and has profound influence on nutrition and health. Two pharmacologically active triterpenoids, β-sitosterol and lupeol, and the powerful flavan-3-ol antioxidant, (+)-catechin, were isolated from the edible fruits of Harpephyllum caffrum while a mixture of cardanols, an alkyl p-coumaric acid ester, and (+)-catechin were isolated from the stem bark. This is the first report of these compounds being isolated from this plant. The antioxidant capacity of (+)-catechin was higher than the other isolated compounds as well as the known antioxidant, ascorbic acid.

Keywords: (+)-catechin; Harpephyllum caffrum; antioxidant activity; cardanol; coumarate; medicinal value.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anacardiaceae / chemistry*
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification*
  • Coumaric Acids / isolation & purification
  • Coumaric Acids / pharmacology
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification
  • Flavonoids / pharmacology
  • Fruit / chemistry
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Pentacyclic Triterpenes / isolation & purification
  • Pentacyclic Triterpenes / pharmacology
  • Phenols / chemistry
  • Phenols / isolation & purification*
  • Phenols / pharmacology*
  • Plant Bark / chemistry
  • Plants, Medicinal / chemistry
  • Propionates
  • Sitosterols / isolation & purification
  • Sitosterols / pharmacology

Substances

  • Antioxidants
  • Coumaric Acids
  • Flavonoids
  • Pentacyclic Triterpenes
  • Phenols
  • Propionates
  • Sitosterols
  • flavan-3-ol
  • gamma-sitosterol
  • p-coumaric acid
  • lupeol