Equine herpesvirus 1 myeloencephalopathy

Vet Clin North Am Equine Pract. 2014 Dec;30(3):489-506. doi: 10.1016/j.cveq.2014.08.006. Epub 2014 Oct 7.

Abstract

Equine myeloencephalopathy (EHM), an uncommon manifestation of equine herpesvirus 1 (EHV-1) infection, can cause devastating losses on individual farms, boarding stables, veterinary hospitals, and show and racing venues. An improved understanding of EHM has emerged from experimental studies and from data collected during field outbreaks at riding schools, racetracks, horse shows, and veterinary hospitals throughout North America and Europe. These outbreaks have highlighted the contagious nature of EHV-1 and have prompted a reevaluation of diagnostic procedures, treatment modalities, preventative measures, and biosecurity protocols for this disease. This article focuses on recent data related to the cause, epidemiology, pathogenesis, immunity, diagnosis, treatment, and prevention of EHV-1 infection with emphasis on EHM.

Keywords: Clinical signs; Diagnosis; Epidemiology; Equine herpesvirus 1; Equine herpesvirus myeloencephalopathy; Etiology; Pathogenesis; Treatment.

Publication types

  • Review

MeSH terms

  • Animals
  • Disease Outbreaks / veterinary
  • Europe / epidemiology
  • Herpesviridae Infections / epidemiology
  • Herpesviridae Infections / therapy
  • Herpesviridae Infections / veterinary*
  • Herpesviridae Infections / virology
  • Herpesvirus 1, Equid / isolation & purification*
  • Horse Diseases / epidemiology
  • Horse Diseases / therapy
  • Horse Diseases / virology*
  • Horses
  • North America / epidemiology