A delicate balance: maintaining mutualism to prevent disease

Daria Van Tyne; Michael S Gilmore

doi:10.1016/j.chom.2014.09.019

A delicate balance: maintaining mutualism to prevent disease

Cell Host Microbe. 2014 Oct 8;16(4):425-7. doi: 10.1016/j.chom.2014.09.019.

Authors

Daria Van Tyne¹, Michael S Gilmore²

Affiliations

¹ Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
² Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: michael_gilmore@meei.harvard.edu.

Abstract

The intestinal microbial ecosystem is complex, and few of the principles that contribute to homeostasis in health are well understood. Pham et al. (2014) show that a network including the epithelial interleukin-22 receptor protects against infection with the opportunistic pathogen Enterococcus faecalis through promotion of host-microbiota mutualism.

A delicate balance: maintaining mutualism to prevent disease

Authors

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Abstract

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