Type 2 diabetes: genotype-based therapy

Sci Transl Med. 2014 Oct 8;6(257):257fs39. doi: 10.1126/scitranslmed.3010687.

Abstract

Targeting a genetic variant with an antagonist may restore insulin secretion in a subgroup of type 2 diabetes patients (Tang et al., this issue).

Publication types

  • Comment

MeSH terms

  • Adrenergic alpha-2 Receptor Antagonists / therapeutic use*
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetes Mellitus, Type 2 / genetics*
  • Female
  • Humans
  • Male
  • Receptors, Adrenergic, alpha-2 / genetics*

Substances

  • ADRA2A protein, human
  • Adrenergic alpha-2 Receptor Antagonists
  • Receptors, Adrenergic, alpha-2