Abstract
A general approach has been developed for the synthesis of spirolactonized Si-rhodamines (SiRBs). The alternative synthetic route provides a facile opportunity to access various s bearing ring-expanded scaffolds and substituents for conjugation. By click reaction, a near-infrared (NIR) mitochondrial tracker was prepared, displaying specific mitochondrial staining in cells.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cell Line, Tumor
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Click Chemistry
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Fluorescent Dyes / chemistry*
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Fluorescent Dyes / pharmacology
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Hep G2 Cells
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Humans
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Mice
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Mitochondria / metabolism
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Rhodamines / chemistry*
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Rhodamines / pharmacology
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Silicon / chemistry*
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Silicon / pharmacology
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Spectrometry, Fluorescence
Substances
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Fluorescent Dyes
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Rhodamines
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Silicon