A short-wavelength infrared emitting multimodal probe for non-invasive visualization of phagocyte cell migration in living mice

Chem Commun (Camb). 2014 Nov 28;50(92):14356-9. doi: 10.1039/c4cc06542e.

Abstract

For the non-invasive visualization of cell migration in deep tissues, we synthesized a short-wavelength infrared (SWIR) emitting multimodal probe that contains PbS/CdS quantum dots, rhodamine 6G and iron oxide nanoparticles. This probe enables multimodal (SWIR fluorescence/magnetic resonance) imaging of phagocyte cell migration in living mice.

MeSH terms

  • Animals
  • Cadmium Compounds* / chemistry
  • Cadmium Compounds* / pharmacology
  • Cell Movement
  • Fluorescent Dyes* / chemistry
  • Fluorescent Dyes* / pharmacology
  • Lead* / chemistry
  • Lead* / pharmacology
  • Lymph Nodes / metabolism
  • Lymphatic Vessels / metabolism
  • Magnetic Resonance Imaging
  • Magnetite Nanoparticles* / administration & dosage
  • Magnetite Nanoparticles* / chemistry
  • Mice
  • Optical Imaging
  • Phagocytes / physiology*
  • Quantum Dots / administration & dosage
  • Quantum Dots / chemistry
  • Rhodamines* / chemistry
  • Rhodamines* / pharmacology
  • Sulfides* / chemistry
  • Sulfides* / pharmacology

Substances

  • Cadmium Compounds
  • Fluorescent Dyes
  • Magnetite Nanoparticles
  • Rhodamines
  • Sulfides
  • rhodamine 6G
  • cadmium sulfide
  • lead sulfide
  • Lead