Abstract
Palladium-catalyzed decarboxylative acylation of highly substituted indolines with α-keto acids via C-H bond activation is described. This protocol provides efficient access to C7-carbonylated indoles known to have diverse biological profiles.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acylation
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Catalysis
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Decarboxylation
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Indoles / chemical synthesis*
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Indoles / chemistry
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Keto Acids / chemistry*
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Molecular Structure
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Palladium / chemistry*
Substances
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Indoles
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Keto Acids
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Palladium
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indoline