When patients on target-specific oral anticoagulants need surgery

Cleve Clin J Med. 2014 Oct;81(10):629-39. doi: 10.3949/ccjm.81a.13168.

Abstract

The target-specific oral anticoagulants (TSOACs), eg, dabigatran, rivaroxaban, and apixaban, are changing the way we manage thromboembolic disease. At the same time, many clinicians wonder how best to manage TSOAC therapy when patients need surgery. An in-depth understanding of these drugs is essential to minimize the risk of bleeding and thrombosis perioperatively.

Publication types

  • Review

MeSH terms

  • Anticoagulants* / classification
  • Anticoagulants* / pharmacology
  • Blood Loss, Surgical / prevention & control*
  • Clinical Protocols
  • Humans
  • Perioperative Care / methods
  • Postoperative Hemorrhage / prevention & control*
  • Surgical Procedures, Operative* / adverse effects
  • Surgical Procedures, Operative* / methods
  • Thromboembolism / prevention & control*

Substances

  • Anticoagulants