Dengue fever in patients admitted in tertiary care hospitals in Pakistan

J Pak Med Assoc. 2014 May;64(5):553-9.

Abstract

Objectives: To assess the gaps in the diagnosis and management of dengue fever cases.

Methods: The retrospective descriptive analytical study was done with a case record analysis of patients with dengue fever admitted from January to December 2010 at five tertiary care hospitals in different Pakistani cities. Using a questionnaire, information was gathered on demography, haematological profile, management, use of blood and platelet transfusions and the outcome. For comparison, data of serologically-confirmed dengue patients from a private laboratory in Islamabad was collected to see the age, gender and month-wise distribution of cases tested over the same period. SPSS 16 was used for statistical analysis.

Results: Out of the 841 confirmed dengue cases, 514 (79%) were males and 139 (21%) females. The overall mean age was 31.3 +/- 14.0 years. Dengue fever was seen in 653 (78%) and dengue haemorrhagic fever (DHF) in 188 (22%) patients. Most cases were between 20 and 49 years of age. A gradual increase in dengue fever and dengue haemorrhagic fever was seen from August, with a peak in October/November. Tourniquet test was done only in 20 (2.3%) cases, out of which 11 (55%) were positive and 9 (45%) were negative. Serial haematocrit was not done in any case. Total deaths were 5 (0.6%).

Conclusions: Most cases were seen in October/November with the majority being in the 20-39 age group. Tourniquet test and serial haematocrit were infrequently used. No standard national guidelines were employed.

MeSH terms

  • Adult
  • Dengue / diagnosis*
  • Dengue / epidemiology
  • Dengue / therapy*
  • Female
  • Hematocrit
  • Humans
  • Male
  • Middle Aged
  • Pakistan / epidemiology
  • Retrospective Studies
  • Seasons
  • Tertiary Care Centers / statistics & numerical data
  • Young Adult