Therapeutic approaches to gastroesophageal junction adenocarcinomas

Ann N Y Acad Sci. 2014 Sep:1325:197-210. doi: 10.1111/nyas.12532.

Abstract

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the distinction between adenocarcinomas above, below, or within the gastroesophageal junction; combined modality therapy; tumor markers for use in personalized medicine; PET-CT and endoscopic biopsies in the evaluation of response to neoadjuvant chemoradiation therapy; a standardized grading system for tumor regression in squamous cell cancer and adenocarcinoma; the experimental basis for new approaches to medical treatment; the criteria measuring response in esophageal cancer; and the impact of novel imaging on staging and response assessment.

Keywords: OESO; PET-CT; combined modality therapy; gastroesophageal junction; tumor grading; tumor markers; tumor regression.

Publication types

  • Congress

MeSH terms

  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / genetics
  • Adenocarcinoma / therapy*
  • Animals
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Biomarkers, Tumor / genetics
  • Esophageal Neoplasms / diagnosis*
  • Esophageal Neoplasms / genetics
  • Esophageal Neoplasms / therapy*
  • Esophagogastric Junction / pathology*
  • Humans
  • Paris
  • Stomach Neoplasms / diagnosis*
  • Stomach Neoplasms / genetics
  • Stomach Neoplasms / therapy*

Substances

  • Biomarkers, Tumor

Supplementary concepts

  • Adenocarcinoma Of Esophagus