Progression of esophageal dysplasia to cancer

Ann N Y Acad Sci. 2014 Sep:1325:96-107. doi: 10.1111/nyas.12523.

Abstract

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the evolution of low-grade squamous and glandular dysplasia to invasive carcinoma; the mutational spectra of Barrett's esophagus and adenocarcinoma; the risk of p53-immunoreactive glandular dysplasia compared to non-immunoreactive mucosa for progression to cancer; the role of lectins in progression to adenocarcinoma; and the role of racemase immunoreactivity in the prediction of risk of adenocarcinoma.

Keywords: Barrett's esophagus; OESO; esophageal adenocarcinoma; lectin; p52; racemase.

Publication types

  • Congress

MeSH terms

  • Animals
  • Barrett Esophagus / blood
  • Barrett Esophagus / complications
  • Barrett Esophagus / diagnosis
  • Disease Progression*
  • Esophageal Neoplasms / blood
  • Esophageal Neoplasms / diagnosis*
  • Esophageal Neoplasms / etiology*
  • Glycoproteins / blood
  • Humans
  • Neoplasm Invasiveness / pathology
  • Paris

Substances

  • Glycoproteins