Super-Refractory Status Epilepticus: Report of a Case and Review of the Literature

Clin EEG Neurosci. 2015 Oct;46(4):335-9. doi: 10.1177/1550059414534418. Epub 2014 Sep 24.

Abstract

Super-refractory status epilepticus (SE; ie, SE continuing or recurring despite 24 hours of general anesthesia) is a severe condition with high percentage of mortality and morbidity. Usually, this condition occurs because of serious brain damage; nevertheless, some patients develop super-refractory SE without identifiable etiology. Although not uncommonly encountered in neurointensive care, scientific data on this condition are still lacking in terms of treatment and prognosis. Herein, we report a case of super-refractory SE with recovery after 50 days, despite electroencephalographic (EEG) and magnetic resonance imaging (MRI) signs traditionally related to poor prognosis. A review of the literature on super-refractory SE is also presented.

Keywords: EEG; MRI; epilepsy; status epilepticus; treatment.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Anticonvulsants / therapeutic use*
  • Diagnosis, Differential
  • Electroencephalography
  • Female
  • Humans
  • Hypnotics and Sedatives / therapeutic use*
  • Magnetic Resonance Imaging
  • Status Epilepticus / diagnosis*
  • Status Epilepticus / drug therapy*

Substances

  • Anticonvulsants
  • Hypnotics and Sedatives