Successful esophagectomy in a patient with combined esophageal cancer and hemophilia B

World J Gastroenterol. 2014 Sep 21;20(35):12701-3. doi: 10.3748/wjg.v20.i35.12701.

Abstract

Patients with esophageal cancer often require esophagectomy with esophagogastrostomy. However, the incidence of complications, such as hemorrhage, during operations for esophageal cancer is high, even with minimally invasive surgery. Without the appropriate interventions, the risk of major intraoperative and postoperative hemorrhage is very high in patients with esophageal cancer and hemophilia. We report the case of a 45-year-old man with esophageal cancer and hemophilia B who underwent a successful hybrid, minimally invasive Ivor-Lewis esophagectomy with appropriate perioperative management.

Keywords: Esophageal cancer; Esophagectomy; Esophagogastrostomy; Hemophilia B; Hemorrhage.

Publication types

  • Case Reports

MeSH terms

  • Blood Coagulation / drug effects*
  • Blood Coagulation Factors / administration & dosage*
  • Blood Coagulation Factors / adverse effects
  • Blood Coagulation Tests
  • Blood Loss, Surgical / prevention & control
  • Carcinoma, Squamous Cell / complications
  • Carcinoma, Squamous Cell / diagnosis
  • Carcinoma, Squamous Cell / surgery*
  • Drug Administration Schedule
  • Esophageal Neoplasms / complications
  • Esophageal Neoplasms / diagnosis
  • Esophageal Neoplasms / surgery*
  • Esophageal Squamous Cell Carcinoma
  • Esophagectomy* / adverse effects
  • Hematinics / administration & dosage*
  • Hematinics / adverse effects
  • Hemophilia B / blood
  • Hemophilia B / complications
  • Hemophilia B / diagnosis
  • Hemophilia B / drug therapy*
  • Humans
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Operative Time
  • Perioperative Care
  • Postoperative Hemorrhage / prevention & control
  • Radiotherapy, Adjuvant
  • Time Factors
  • Treatment Outcome

Substances

  • Blood Coagulation Factors
  • Hematinics
  • prothrombin complex concentrates