Tenosynovitis caused by a novel nontuberculous Mycobacterium species initially misidentified as a member of the Mycobacterium tuberculosis complex

J Clin Microbiol. 2014 Dec;52(12):4414-8. doi: 10.1128/JCM.00967-14. Epub 2014 Sep 24.

Abstract

We present a case of tenosynovitis caused by a novel, slowly growing, nonchromogenic, nontuberculous mycobacterium (NTM). Originally misidentified as Mycobacterium tuberculosis complex, the NTM cross-reacts with the M. tuberculosis complex nucleic acid hybridization probe, a M. tuberculosis gamma interferon release assay, and is closely related to M. tuberculosis by 16S rRNA gene sequencing.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Cluster Analysis
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Diagnostic Errors
  • Diagnostic Tests, Routine
  • Female
  • Humans
  • Interferon-gamma Release Tests
  • Middle Aged
  • Molecular Sequence Data
  • Mycobacterium Infections, Nontuberculous / diagnosis*
  • Mycobacterium Infections, Nontuberculous / microbiology*
  • Mycobacterium Infections, Nontuberculous / pathology
  • Nontuberculous Mycobacteria / classification
  • Nontuberculous Mycobacteria / genetics
  • Nontuberculous Mycobacteria / isolation & purification*
  • Nucleic Acid Hybridization
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA
  • Tenosynovitis / diagnosis*
  • Tenosynovitis / microbiology*
  • Tenosynovitis / pathology

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Ribosomal, 16S

Associated data

  • GENBANK/KF683289
  • GENBANK/KJ371034
  • GENBANK/KJ371036