(5R*)-5-[(2S*,5S*)-1-Meth-oxy-5-phenyl-pyrrolidin-2-yl]-3-methyl-furan-2(5H)-one

Takeshi Oishi; Makoto Yoritate; Takaaki Sato; Noritaka Chida

doi:10.1107/S1600536814014974

(5R)-5-[(2S,5S*)-1-Meth-oxy-5-phenyl-pyrrolidin-2-yl]-3-methyl-furan-2(5H)-one

Acta Crystallogr Sect E Struct Rep Online. 2014 Jul 2;70(Pt 8):o839. doi: 10.1107/S1600536814014974. eCollection 2014 Aug 1.

Authors

Takeshi Oishi¹, Makoto Yoritate², Takaaki Sato², Noritaka Chida²

Affiliations

¹ School of Medicine, Keio University, Hiyoshi 4-1-1, Kohoku-ku, Yokohama 223-8521, Japan.
² Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi 3-14-1, Kohoku-ku, Yokohama 223-8522, Japan.

Abstract

In the title compound, C16H19NO3, the pyrrolidine ring is in a twist conformation. The dihedral angle between the di-hydro-furan ring [maximum deviation = 0.0016 (11) Å] and the phenyl ring is 47.22 (8)°. In the crystal, mol-ecules are linked by weak C-H⋯O hydrogen bonds, forming helical chains along the b-axis direction. The chains are further linked by C-H⋯π inter-actions to constitute a three-dimensional architecture.

Keywords: crystal structure.