Cytarabine preferentially induces mutation at specific sequences in the genome which are identifiable in relapsed acute myeloid leukaemia

Leukemia. 2015 Feb;29(2):491-4. doi: 10.1038/leu.2014.284. Epub 2014 Sep 24.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Antimetabolites, Antineoplastic / adverse effects
  • Cell Line, Tumor
  • Cytarabine / adverse effects
  • Cytarabine / chemistry*
  • DNA Mutational Analysis
  • Humans
  • Leukemia, Myeloid, Acute / diagnosis
  • Leukemia, Myeloid, Acute / drug therapy*
  • Leukemia, Myeloid, Acute / genetics*
  • Monte Carlo Method
  • Mutation*
  • Neoplasm Recurrence, Local / genetics*
  • Remission Induction

Substances

  • Antimetabolites, Antineoplastic
  • Cytarabine