Re and (99m)Tc complexes of BodP3--multi-modality imaging probes

Chem Commun (Camb). 2014 Dec 21;50(98):15503-5. doi: 10.1039/c4cc06367h. Epub 2014 Sep 24.

Abstract

A fluorescent tridentate phosphine, BodP3 (2), forms rhenium complexes which effectively image cancer cells. Related technetium analogues are also readily prepared and have potential as dual SPECT/fluorescent biological probes.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Coordination Complexes* / analysis
  • Crystallography, X-Ray
  • Fluorescent Dyes* / analysis
  • Humans
  • Male
  • Models, Molecular
  • Multimodal Imaging*
  • Optical Imaging*
  • Phosphines / analysis
  • Prostatic Neoplasms / diagnosis
  • Rhenium* / analysis
  • Technetium* / analysis
  • Tomography, Emission-Computed, Single-Photon*

Substances

  • Coordination Complexes
  • Fluorescent Dyes
  • Phosphines
  • Rhenium
  • Technetium
  • phosphine