Abstract
Both convergent and divergent strategies for the synthesis of "onion peel" glycodendrimers are reported which resulted in one of the best multivalent ligands known against the virulent factor from a bacterial lectin isolated from Pseudomonas aeruginosa.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Dendrimers / chemical synthesis*
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Dendrimers / chemistry*
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Dendrimers / pharmacology
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Glycerides / chemical synthesis*
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Glycerides / chemistry*
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Glycerides / pharmacology
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Lectins / chemistry
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Ligands
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Molecular Structure
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Pseudomonas aeruginosa / chemistry
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Virulence Factors / antagonists & inhibitors
Substances
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Dendrimers
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Glycerides
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Lectins
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Ligands
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Virulence Factors