Pharmacological treatment of panic disorder

Mod Trends Pharmacopsychiatry. 2013:29:128-43. doi: 10.1159/000351953. Epub 2013 Sep 20.

Abstract

A comprehensive database has developed and precise recommendations can be provided for treating patients with panic disorder. Selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors are standard treatments for panic disorder. Tricyclic antidepressants are as effective as modern antidepressants, but less well tolerated. For short-term treatment and in non-responsive cases, benzodiazepines such as alprazolam may be used when the patient does not have a history of dependency and tolerance. Combining drug treatment with cognitive behaviour therapy is the most successful treatment strategy for panic disorder. This chapter also includes treatment recommendations for pregnant or lactating women, children, adolescents, elderly patients, and patients who are non-responsive to standard treatments.

Publication types

  • Review

MeSH terms

  • Antidepressive Agents / therapeutic use*
  • Benzodiazepines
  • Child
  • Drug Therapy / methods*
  • Drug Therapy / standards
  • Female
  • Humans
  • Male
  • Monoamine Oxidase Inhibitors
  • Panic Disorder / drug therapy*
  • Pregnancy
  • Selective Serotonin Reuptake Inhibitors

Substances

  • Antidepressive Agents
  • Monoamine Oxidase Inhibitors
  • Serotonin Uptake Inhibitors
  • Benzodiazepines