Femtosecond laser-assisted sutureless anterior lamellar keratoplasty for superficial corneal opacities

J Cataract Refract Surg. 2014 Nov;40(11):1805-12. doi: 10.1016/j.jcrs.2014.02.044. Epub 2014 Sep 11.

Abstract

Purpose: To evaluate the visual and refractive outcomes, endothelial cell count (ECC), ocular surface changes, corneal aberrations, and biomechanical profile changes after femtosecond laser-assisted anterior lamellar keratoplasty surgery for superficial corneal scars.

Setting: Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Design: Prospective case series.

Methods: Patients with superficial corneal scars had femtosecond laser-assisted anterior lamellar keratoplasty. Visual and refractive results, ECC, ocular surface changes, corneal aberrations, and biomechanical profiles were assessed preoperatively and for 1 year postoperatively.

Results: Nineteen eyes (19 patients) were evaluated. A significant decline occurred in refractive astigmatism and corneal astigmatism after 1 year. There was a nonsignificant reduction in corneal hysteresis and the corneal resistance factor from preoperatively to 1 year postoperatively. The corneal-compensated intraocular pressure (IOP) and Goldmann-correlated IOP increased during the follow-up; the increase was not significant. A statistically insignificant reduction in the root mean square for trefoil and spherical aberrations occurred between 1 month and 1 year postoperatively (P=.1 and P=.4, respectively). The decreases in primary coma and total higher-order aberrations approached significance (P=.08 and P=.07, respectively). There were no significant changes in the central corneal thickness, ECC, or ocular surface parameters. No intraoperative complications occurred.

Conclusion: Femtosecond laser-assisted anterior lamellar keratoplasty was an efficient and safe procedure for improving the quality of vision in patients with anterior corneal pathology, and the results remained stable during the 1-year follow-up.

Financial disclosure: No author has a financial or proprietary interest in any material or method mentioned.

MeSH terms

  • Adult
  • Cell Count
  • Corneal Opacity / diagnosis
  • Corneal Opacity / surgery*
  • Corneal Surgery, Laser / methods*
  • Corneal Transplantation / methods*
  • Endothelium, Corneal / pathology
  • Humans
  • Intraocular Pressure / physiology
  • Prospective Studies
  • Refraction, Ocular / physiology
  • Suture Techniques
  • Tomography, Optical Coherence
  • Visual Acuity / physiology