Chemical stability of (99m)Tc-DTPA under aerobic and microbially mediated Fe(III)-reducing conditions in porous media

Appl Radiat Isot. 2014 Dec:94:175-181. doi: 10.1016/j.apradiso.2014.08.005. Epub 2014 Aug 19.

Abstract

(99m)Tc-DTPA has been used as a conservative tracer to quantify water transport through porous media. However, more information on the reactivity of this (99m)Tc compound under varying geochemical conditions is desirable to better understand its potential uses. We measured the speciation of Tc following amendment of (99m)Tc-DTPA to batch systems spanning a range of controlled biogeochemical conditions. Our results suggest that (99m)Tc-DTPA is stable under the reducing conditions tested. However, freshly precipitated Al-ferrihydrite may displace Tc(IV) from DTPA in the absence of Fe(III)-reducing conditions.

Keywords: Chromium; Groundwater; Radiotracer; SPECT; Technetium; Tomography.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Biodegradation, Environmental
  • Drug Stability
  • Groundwater / chemistry*
  • Groundwater / microbiology*
  • Iron / chemistry*
  • Iron / metabolism*
  • Porosity
  • Shewanella putrefaciens / chemistry*
  • Shewanella putrefaciens / metabolism*
  • Technetium Tc 99m Pentetate / analysis
  • Technetium Tc 99m Pentetate / chemistry*

Substances

  • Iron
  • Technetium Tc 99m Pentetate