Effects of oral Enterococcus faecium strain DSM 10663 NCIMB 10415 on diarrhoea patterns and performance of sucking piglets

Benef Microbes. 2015 Mar;6(1):41-4. doi: 10.3920/BM2014.0008.

Abstract

Effects of probiotic Enterococcus faecium DMS 10663 NCIMB 10415 on diarrhoea and performance of sucking piglets were evaluated in a double-blind, placebo-controlled study. Piglets from treatment group (TG, n=56) and placebo group (PG, n=53) sows were included in the study. Immediately after birth and at day 2 and 3 post natum, each of the TG piglets received 2.8×10(9) colony forming units (cfu) per os. From day 4 until weaning (day 26), 1.26×10(9) cfu E. faecium/piglet were given twice a day via a liquid additive. Piglets already suffering from diarrhoea additionally got a glucose-electrolyte solution enriched with 2.9×10(8) (week 1) and 5.8×10(8) (week 2) cfu E. faecium/day. PG piglets received corresponding placebo preparations. A score was defined to characterise the severity of diarrhoea, including accompanying symptoms. The counts of viable born, stillborn and weaned piglets were similar in TG and PG litters (P>0.05). The probiotic treatment mitigated incidence and severity of diarrhoea (P<0.05) with no impact on diarrhoea length (P>0.05). Probiotic treatment improved daily weight gain (P<0.05) yet with no provable effect on body weight at weaning (P>0.05). The additional supply of E. faecium in piglets suffering from diarrhoea had no further beneficial effect.

Keywords: Enterococcus faecium; pig; probiotic; weight gain.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Animals
  • Biological Therapy / methods*
  • Diarrhea / pathology
  • Diarrhea / therapy
  • Diarrhea / veterinary*
  • Double-Blind Method
  • Enterococcus faecium / growth & development*
  • Placebos / administration & dosage
  • Probiotics / administration & dosage*
  • Severity of Illness Index
  • Swine
  • Swine Diseases / pathology
  • Swine Diseases / therapy*
  • Treatment Outcome

Substances

  • Placebos