Synthesis and characterisation of glucosamine-NSAID bioconjugates

Org Biomol Chem. 2014 Nov 7;12(41):8325-35. doi: 10.1039/c4ob01681e. Epub 2014 Sep 12.

Abstract

Strategies to couple non-steroidal anti-inflammatory drugs (NSAIDs) to a glucosamine hydrochloride salt via an amino acid linker are investigated and a series of novel NSAID-glucosamine bioconjugates have been prepared.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids / chemistry
  • Anti-Inflammatory Agents, Non-Steroidal / chemical synthesis
  • Anti-Inflammatory Agents, Non-Steroidal / chemistry*
  • Glucosamine / chemistry*
  • Molecular Structure

Substances

  • Amino Acids
  • Anti-Inflammatory Agents, Non-Steroidal
  • Glucosamine