Dosimetric analysis between carbon ion radiotherapy and stereotactic body radiotherapy in stage I lung cancer

Abstract

Aim: To evaluate dosimetric differences between carbon ion radiotherapy (C-ion RT) and stereotactic body radiotherapy (SBRT) for stage I non-small cell lung cancer (NSCLC).

Patients and methods: Thirteen stage I NSCLC cases were planned with C-ion RT and SBRT. Prescription of the dose and fractionation (fr) for stage IA and IB in C-ion RT were 52.8 Gy (RBE)/4fr and 60.0 Gy (RBE)/4fr, respectively and those in SBRT were 52.8 Gy/4fr and 60.0 Gy/4fr, respectively.

Results: The conformity index (CI) for planning target volume of C-ion RT was significantly lower than that of SBRT. The normal lung doses in C-ion RT were significantly lower those that in SBRT. In particularly, for a larger tumor, C-ion RT was lower CI and normal lung dose than SBRT.

Conclusion: C-ion RT has an advantage in both target conformity and sparing of normal lung in stage I NSCLC.

Keywords: Dosimetric analysis; carbon ion radiotherapy; stage I non-small cell lung cancer; stereotactic body radiotherapy.