Experimental comparison of chiral metal-organic framework used as stationary phase in chromatography

Sheng-Ming Xie; Mei Zhang; Zhi-Xin Fei; Li-Ming Yuan

doi:10.1016/j.chroma.2014.08.059

Experimental comparison of chiral metal-organic framework used as stationary phase in chromatography

J Chromatogr A. 2014 Oct 10:1363:137-43. doi: 10.1016/j.chroma.2014.08.059. Epub 2014 Aug 23.

Authors

Sheng-Ming Xie¹, Mei Zhang², Zhi-Xin Fei¹, Li-Ming Yuan³

Affiliations

¹ Department of Chemistry, Yunnan Normal University, Kunming 650500, PR China.
² Department of Pharmacy, Yunnan University of Traditional Chinese Medicine, Kunming 650500, PR China.
³ Department of Chemistry, Yunnan Normal University, Kunming 650500, PR China. Electronic address: yuan_limingpd@126.com.

PMID: 25200532
DOI: 10.1016/j.chroma.2014.08.059

Abstract

Chiral metal-organic frameworks (MOFs) are a new class of multifunctional material, which possess diverse structures and unusual properties such as high surface area, uniform and permanent cavities, as well as good chemical and thermal stability. Their chiral functionality makes them attractive as novel enantioselective adsorbents and stationary phases in separation science. In this paper, the experimental comparison of a chiral MOF [In₃O(obb)₃(HCO₂)(H₂O)] solvent used as a stationary phase was investigated in gas chromatography (GC), high-performance liquid chromatography (HPLC) and capillary electrochromatography (CEC). The potential relationship between the structure and components of chiral MOFs with their chiral recognition ability and selectivity are presented.

Keywords: Capillary electrochromatography; Chiral stationary phase; Gas chromatography; High-performance liquid chromatography; Metal-organic frameworks.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Chromatography / methods*
Metals / chemistry*
Organic Chemicals / chemistry*

Substances

Metals
Organic Chemicals