[Radiological evaluation of the tumour response after lung stereotactic radiotherapy]

Cancer Radiother. 2014 Oct;18(5-6):414-9. doi: 10.1016/j.canrad.2014.07.157. Epub 2014 Sep 16.
[Article in French]

Abstract

Stereotactic body radiotherapy is the treatment of choice for medically non-operable T1-T2 N0M0 non-small cell lung cancer or for slowly growing lung metastases with no evolutive primary tumour. Lung stereotactic radiotherapy provides an excellent local control rate, higher than 80%. Nevertheless, although the clinical toxicity rate is less than 5%, postradiation radiological reactions surrounding the tumour, called "radiological radiation pneumonitis", are very frequent, which makes it difficult to evaluate the tumour response. Firstly, this review describes the lesions of acute and chronic radiation pneumonitis and the CT images suggesting a local recurrence. Then, we evaluated the place of PET after stereotactic body radiotherapy in the follow-up period. Finally, we suggest an algorithm helping physicians in the follow-up of such treated patients.

Keywords: Carcinome bronchique non à petites cellules; Lung metastases; Métastases pulmonaires; Non-small cell lung cancer; Pneumopathie radique; Radiation pneumonitis; Radiothérapie stéréotaxique; Stereotactic body radiotherapy.

Publication types

  • Review

MeSH terms

  • Aftercare
  • Algorithms
  • Carcinoma, Non-Small-Cell Lung / surgery*
  • Diagnosis, Differential
  • Disease-Free Survival
  • Fluorine Radioisotopes
  • Fluorodeoxyglucose F18
  • Humans
  • Incidence
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / secondary
  • Lung Neoplasms / surgery*
  • Neoplasm Recurrence, Local / diagnostic imaging
  • Positron-Emission Tomography
  • Radiation Injuries
  • Radiation Pneumonitis / diagnostic imaging*
  • Radiation Pneumonitis / epidemiology
  • Radiation Pneumonitis / etiology
  • Radiation Pneumonitis / prevention & control
  • Radiopharmaceuticals
  • Radiosurgery / adverse effects*
  • Time Factors
  • Tomography, X-Ray Computed / methods*
  • Treatment Outcome

Substances

  • Fluorine Radioisotopes
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18