Relationship Between Alcohol Consumption and Serum Lipid Profiles Among Middle-Aged Population in China: A Multiple-Center Cardiovascular Epidemiological Study

Angiology. 2015 Sep;66(8):753-8. doi: 10.1177/0003319714549557. Epub 2014 Sep 4.

Abstract

We assessed the relationship between alcohol consumption and serum lipids in a middle-aged Chinese population. The overall prevalence of drinking among 10 154 participants was 34.07% in males and 3.61% in females. Heavy alcohol drinkers (≥ 30 g/d) tended to be older, smokers, hypertensive, do heavy physical activity, and have a lower body mass index. Levels of high-density lipoprotein cholesterol (HDL-C), apolipoprotein (apo) A1, low-density lipoprotein cholesterol-HDL-C ratio, and apo B-apo A1 ratio rose with increase in alcohol intake in males. An increase of 0.27 mmol/L in triglycerides and a decrease of 2.10 mg/dL in lipoprotein(a), Lp(a), were observed in male alcohol drinkers who consumed ≥30 g alcohol/d compared with abstainers after controlling for all confounders. Levels of total cholesterol, HDL-C, and apo A1 increased with increase in alcohol intake in both genders and Lp(a) decreased with the increase in alcohol intake in males.

Keywords: China; alcohol; association; serum lipid.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Alcohol Drinking / adverse effects
  • Alcohol Drinking / blood*
  • Alcohol Drinking / epidemiology*
  • Apolipoprotein A-I / blood
  • Apolipoprotein B-100 / blood
  • Biomarkers / blood
  • Body Mass Index
  • China / epidemiology
  • Cholesterol, HDL / blood
  • Comorbidity
  • Cross-Sectional Studies
  • Dyslipidemias / blood*
  • Dyslipidemias / diagnosis
  • Dyslipidemias / epidemiology*
  • Female
  • Humans
  • Hypertension / epidemiology
  • Lipids / blood*
  • Lipoprotein(a) / blood
  • Male
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Smoking / adverse effects
  • Smoking / blood
  • Smoking / epidemiology
  • Triglycerides / blood

Substances

  • APOA1 protein, human
  • APOB protein, human
  • Apolipoprotein A-I
  • Apolipoprotein B-100
  • Biomarkers
  • Cholesterol, HDL
  • Lipids
  • Lipoprotein(a)
  • Triglycerides