Transient abnormal myelopoiesis/acute megakaryoblastic leukemia diagnosed in the placenta of a stillborn Down syndrome fetus with targeted next-generation sequencing

Leukemia. 2015 Jan;29(1):232-3. doi: 10.1038/leu.2014.258. Epub 2014 Sep 2.

Authors

B Federmann¹, A Fasan², K O Kagan³, S Haen¹, F Fend¹

Affiliations

¹ Institute of Pathology and Neuropathology, Comprehensive Cancer Center and University Hospital Tuebingen, Tuebingen, Germany.
² MLL Munich Leukemia Laboratory, Munich, Germany.
³ Department of Obstetrics and Gynaecology, Comprehensive Cancer Center and University Hospital Tuebingen, Tuebingen, Germany.

PMID: 25179734
DOI: 10.1038/leu.2014.258

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Female
Fetal Diseases / diagnosis*
Fetal Diseases / genetics
Humans
Leukemia, Megakaryoblastic, Acute / diagnosis*
Leukemia, Megakaryoblastic, Acute / genetics
Myelopoiesis*
Placenta / pathology*
Pregnancy
Sequence Analysis / methods*
Stillbirth*