Halo naevi and café au lait macule regression in a renal transplant patient on immunosuppression

Abstract

A case of halo naevi and café au lait macule regression in a renal transplant patient receiving long-term immunosuppressive therapy is described. We propose the direct transfer of an auto-reactive antibody, CD8 T-cells or tumour necrosis factor α from the transplant donor to the recipient as a possible cause. We have also considered insufficient immunosuppressive therapy as a possible mechanism.

Keywords: alopecia; depigmentation; halo naevi; immunosuppression; renal transplant; vitiligo.